Aggarwal and his team identified the shape of the enzymes in a short amount of time and immediately made their results available to researchers throughout the world working to find an effective treatment for Zika virus. The next step would be to develop compounds to inhibit these enzymes actions by physically blocking them, interfering with the reproduction of the virus, said Dr. Aggarwal. my linkWe are fortunate to be able to collaborate with some of the best computational and medicinal chemists and virologists right here at Mount Sinai. The Zika virus has emerged as a major health concern over the past year, spreading rapidly across parts of South and Central America, as well as some parts of North America. It has been linked to birth defects in newborn infants and Guillain-Barre syndrome in adults. At this point, there is no effective way of preventing infection once people are exposed to Zika-carrying mosquitoes. We hope this work will lead to the development of effective treatments that help alleviate the terrible effects of Zika, and we see ourselves as part of a world-wide effort, said Dr. Aggarwal. About the Mount Sinai Health System The Mount Sinai Health System is an integrated health system committed to providing distinguished care, conducting transformative research, and advancing biomedical education. Structured around seven hospital campuses and a single medical school, the Health System has an extensive ambulatory network and a range of inpatient and outpatient servicesfrom community-based facilities to tertiary and quaternary care. The System includes approximately 7,100 primary and specialty care physicians; 12 joint-venture ambulatory surgery centers; more than 140 ambulatory practices throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and 31 affiliated community health centers.interview skills app
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Recreational divers should consider consulting with their dentist before diving if they recently received dental care. Credit: Image courtesy of University at Buffalo Vinisha Ranna, BDS, lead author and certified stress and rescue scuba diver, swims near underwater wreckage in Sri Lanka. Credit: Image courtesy of University at Buffalo Close Scuba divers may want to stop by their dentist’s office before taking their next plunge. A new pilot study found that 41 percent of divers experienced dental symptoms in the water, according to new research from the University at Buffalo. Due to the constant jaw clenching and fluctuations in the atmospheric pressure underwater, divers may experience symptoms that range from tooth, jaw and gum pain to loosened crowns and broken dental fillings. Recreational divers should consider consulting with their dentist before diving if they recently received dental care, says Vinisha Ranna, BDS, lead author and a student in the UB School of Dental Medicine. “Divers are required to meet a standard of medical fitness before certification, but there are no dental health prerequisites,” says Ranna, who is also a certified stress and rescue scuba diver. “Considering the air supply regulator is held in the mouth, any disorder in the oral cavity can potentially increase the diver’s risk of injury. A dentist can look and see if diving is affecting a patient’s oral health.” The study, “Prevalence of dental problems in recreational SCUBA divers,” was published last month in the British Dental Journal.
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